产品货号：
Z17895
中文名称：
HSP70抗体
英文名称：
Anti-HSP70 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSP70 Antibody |
| 指标别名 | HSP70;HSP70 1;HSP70 1/HSP70 2;HSP70 1A;HSP70.1/HSP70.2;HSP70I;HSP72;HSPA1;HSPA1A;HSPA1B;HSP70;HSP70 1/HSP70 2;HSP70 1B;HSP70 2;HSPA1;HSPA1A;HSPA1B |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,IHC-F,ICC |
| 基因名称 | HSPA1A/HSPA1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp70(577-596aa VISWLDANTLAEKDEFEHKR),different from the related mouse sequence by four amino acids and from the related rat sequence by three amino acids. |
| 实际分子量 | 70KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSPA1(heat shock 70kDa protein 1A) also known as HSP70-1,HSPA1A,HSP70-1A,HSP72 or HSP70I,is a protein that in humans is encoded by the HSPA1A gene.This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family.The HSPA1A gene encodes a predicted 641-amino acid protein.The HSPA1 gene is mapped on 6p21.33.Shimizu et al.(1999) found that peripheral blood mononuclear cells of 18 major depression patients expressed a short HSPA1A transcript that utilized exon 1 rather than exon 2,which is found in the more common HSPA1A transcript.No protein was associated with expression of this short HSPA1A mRNA,possibly due to lack of a TATA box or loss of internal ribosome binding sites.Treatment with BGP-15,a pharmacologic inducer of Hsp72 that can protect against obesity-induced insulin resistance,improved muscular architecture,strength,and contractile function in severely affected diaphragm muscles in mdx dystrophic mice. |
| Uniprot ID | P0DMV8/P0DMV9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | heat shock protein family A (Hsp70) member 1A/1B |
| 蛋白名全称 | Heat shock 70kDa protein 1A/1B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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